| Famous Alumni | |
- Frederic Lauriston Bullard – Pulitzer Prize-winning journalist for the Boston Herald, Lincoln historian, writer ("Famous War Correspondents")
- Christine Camp – deputy press secretary for George McGovern
- Vince Cellini – current host on The Golf Channel and former anchor for CNN Sports
- Arthur Holly Compton – Nobel Prize-winning physicist, member of the National Academy of Sciences, former chancellor of Washington University from 1945 to 1953
- Karl Taylor Compton – president of MIT from 1930 to 1948, member of the National Academy of Sciences
- Mary Crow – Colorado Poet Laureate
- John Dean – White House Counsel (1970–1973) to President Richard Nixon
- Eugene DePasquale – member of the Pennsylvania House of Representatives
- Stephen R. Donaldson – New York Times bestselling science fiction author ("Thomas Covenant")
- Helen Murray Free – elected president of the American Chemical Society in 1993, inducted into the National Inventors Hall of Fame in 2000
- Stanley Gault – former CEO of Rubbermaid, Goodyear Tire and Rubber Company
- Duncan Jones – English film director, best known for "Moon" (2009) and "Source Code" (2011)
- John McSweeney – member of the United States House of Representatives
- Blake Moore – former NFL lineman for the Cincinnati Bengals and Green Bay Packers, CEO of Allianz Global Investors
- Timothy Smucker – CEO of The J.M. Smucker Co.
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